Evaluation effects of Bifidobacterim bifidum (BIB2) on man endurance swimmers Immunoglobulin A and CD4 cells count

چکیده مقاله

Background and aim: It is necessary to enhance athletes’ immune system functions with the probiotics supplemented foods. They help body health; consequently, it decreases health maintenance costs for athletes. Probiotics improve immune system functions against pathogens via affecting on innate immune system, humoral immunity and cytokines. In this research, we evaluated effects of consumption of Iranian probiotic Bifidobactrium bifidum (BIB2) on athletes’ immune system functions.
Material and methods: This research was done according to the double blind study. First, 40 Swimmer male volunteers, the age limit of 18 to 22 and 68 to 75 weigh individuals were divided in two groups. Second, one of them received fruit juice supplemented with Bifidobactrium bifidum (BIB2) and the other group had only fruit juice as control. Blood samples were collected each 15 days for 8 weeks. Then, IgA level and CD4 positive cells count were measured by ELISA kit and flow cytometry.
Results: The results of IgA and CD4 measurements showed significant increase (p<0.05) in test group compared with control group.
Conclusion: Probiotics consumption affected immune system functions and improve general health via increasing IgA level and CD4 cells count.

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