For many decades open surgery remained the only way available for local control of body tumors. In order to decrease the patients’ morbidity and mortality several image guided minimally invasive procedures have been adopted. High intensity focused ultrasound (HIFU) or focused ultrasound (FUS) is a promising modality to treat tumors in a complete, noninvasive fashion where online image guidance and therapy control can be achieved by magnetic resonance imaging (MRI) or diagnostic ultrasound (US). In the last 10 years, the feasibility and the safety of HIFU have been tested in a growing number of clinical studies on several benign and malignant tumors of the prostate, breast, uterine, liver, kidney, pancreas, bone, and brain. The therapeutic potential of HIFU lies in the fact that it enables the localized deposition of high-energy doses deep within the human body without harming the surrounding tissue. The clinical and preclinical applications of HIFU range from the thermal treatment of benign and malign lesions, targeted drug delivery, to the treatment of thrombi. The advances in HIFU technology during the past two decades expanded the HIFU applications to include ablation of both benign and malignant tumors with different treatment strategies being implemented for each type. The aim of this review is to introduce the reader to the details of the treatment process including pretreatment preparation, treatment planning, different ablation strategies, patients’ after care as well as the follow up regimens for the most common HIFU applications.
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Yousof Kamari؛Mona Hajiasgari؛Hamidreza Chabok؛Mahsa Naghieh؛ Neda Kaffash؛ ۱۳۹۵، high-intensity focused ultrasound applications as a novel treatment for brain tumors: A survey، ششمین کنفرانس بین المللی پژوهش در مهندسی،علوم و تکنولوژِی، https://scholar.conference.ac:443/index.php/download/file/12859-high-intensity-focused-ultrasound-applications-as-a-novel-treatment-for-brain-tumors:-A-survey
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(Yousof Kamari؛Mona Hajiasgari؛Hamidreza Chabok؛Mahsa Naghieh؛ Neda Kaffash؛ ۱۳۹۵)